mature TGF-beta 1 Species_Methylorubrum extorquens Sabine Kespohl

Sabine Kespohl

PETRRSIEVPLNERICLQVGSQCSTNESEKPSILVEKCISPPEGDPESAVTELQCIWHNLSYMK

Sequence without tags (AA 16-270): MSGYGPPSSHSSSRVVHGEDAVPYSWPWQVSLQYEKSGSFYHTCGGSLIAPDWVVTAGHCISRDLT  YQVVLGEYNLAVKEGPEQVIPINSEELFVHPLWNRSCVACGNDIALIKLSRSAQLGDAVQLASLPPAG  DILPNKTPCYITGWGRLYTNGPLPDKLQQARLPVVDYKHCSRWNWWGSTVKKTMVCAGGYIRSGC  NGDAGGPLNCPTEDGGWQVHGVTSFVSAFGCNFIWKPTVFTRVSAFIDWIEETIASHVLVPRGSAAALE

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mature TGF-beta 1 Species_Methylorubrum extorquens Sabine KespohlTransforming growth factor beta 1 (TGF 1) is a pleiotropic cytokine involved in a myriad of cellular functions, including cell growth, differentiation, immune regulation and tissue homeostasis. It is a member of the TGF superfamily and exerts its effects by binding to specific cell surface receptors, thereby activating intracellular signaling pathways that mediate regulatory signals, controlling expression of target genes. Dysregulation of TGF 1 is